Definition, diagnosis and classification of diabetes. Pathophysiology of type 2 diabetes and its treatment policy. Diagnosis, acute and chronic complications, and treatment of diabetes are. Acute and chronic complications acute diabetic ketoacidosis dka hyperglycemic hyperosmolaris syndrome hhs. Diabetes, correctly termed diabetes mellitus, is a major ep idemic of this century. New guidelines for the diagnosis of diabetes mellitus. Diabetes mellitus complications 2008 the prudential insurance company of america 751 broad street, newark, nj 071023777 rx0 ifsa120680 ed. Diabetes mellitus diabetes diagnosed during pregnancy immediately after pregnancy. Diabetes mellitusinduced microvascular destabilization in. Insulin therapy is recommended for patients with type 2 diabetes mellitus and an initial a1c level greater than. Diabetes mellitus professor mamdouh elnahas professor of internal medicine endocrinology and diabetes unit. Review article diabetes mellitus a devastating metabolic. The objective was to assess the effect of treatment for mild gdm on the bmi of 4 to 5year. The treatment of type 2 diabetes also can produce symptoms.
Diabetes mellitus is an endocrinological andor metabolic disorder with an increasing global prevalence and incidence. Diabetes mellitus samreen riaz department of microbiology and molecular genetics, punjab university, new campus, lahore. When you eat a carbohydrate, your body turns it into a sugar called. Abstract diabetes mellitus type 2 is a disease that affect millions of people worl. Insulin controls how much sugar stays in your blood. Compare and contrast type 1 and 2 diabetes presentation, onset, progression, and pathophysiology. I have proposed a merge between honeymoon period diabetes and this article, as i believe the majority of the content covered in the merged article is covered here, and any remaining. Diabetes mellitus an easy to understand guide covering causes, diagnosis, symptoms, treatment and prevention plus additional in depth medical information. Tgfb and diabetes mellitus 3 access to food, water and an environment free of certain germs. Diabetes mellitus type 2 statpearls ncbi bookshelf. Smoking also causes oxidative stress, a condition that occurs as chemicals from cigarette smoke combine with oxygen in the body. Whilst the different types of diabetes share a number of common symptoms, the causes of each type of diabetes can vary quite considerably. Objective gestational diabetes mellitus gdm may cause obesity in the offspring.
Diabetes mellitus is defined as a cluster of metabolic disorders, characterized by hyperglycemia high enough to significantly increase the incidence of a specific an unique type of microangiopathy. People who have diabetes fall into one of two categories, referred to as type 1 and 2. Pdf diabetes, often referred to by doctors as diabetes mellitus, describes a group of metabolic diseases in which the. Hypertriglyceridemia can be caused by primary genetic mutations, secondary causes, such as uncontrolled diabetes, obesity, alcohol overuse, or combinations of both. The terminology diabetes mellitus dm means a conglomerate of disorders involving unusual fat, protein, and carbohydrate digestion that eventually causes acute and chronic manifestations because of. For these reasons, hba1c is suitable as a primary diagnostic tool for excluding diabetes with great certainty and for making a diagnosis of diabetes in some cases. Thechronichyperglycemia of diabetes is associated with longterm damage, dysfunction, and failure of. Diabetes mellitus is a very common disorder in all over the world, often simply referred to as diabetes, is a group of metabolic diseases also known as metabolic syndrome and a slow poison in. Repercussions of diabetes mellitus on the oral cavity. Diabetes mellitus definition of diabetes mellitus by. Risk factors contributing to type 2 diabetes and recent advances.
Pdf diabetes mellitus can be viewed as an outcome of the interplay among the. Diabetes mellitus definition and description of diabetes mellitus diabetes is a group of metabolic diseases characterized by hyperglycemia resulting fromdefectsininsulinsecretion,insulinaction,orboth. Its also possible to combine tablets and injections. Diabetes mellitus has now assumed epidemic proportions in many countries of the world. Type 2 diabetes and its complications constitute a major worldwide public health problem. Effect of treatment of gestational diabetes mellitus on. Blood sugar levels that are always too high may cause the following symptoms, though.
If the offspring is female, she is likely to develop gdm. Type 2 diabetes was previously called noninsulindependent diabetes mellitus niddm or adultonset diabetes. Accepted 16 april, 2009 diabetes is a lifelong disease marked by elevated levels of sugar in the blood. Management of vadod clinical practice guidelines home. Type 1 diabetes is a common, multifactorial disease with strong familial clustering genetic risk ratio. Targeting and monitoring glycemic control in nonpregnant adults with diabetes mellitus. As the population increases, including growing subpopulations of obese and elderly individuals, type 2. Diabetes is one of the leading causes of blindness, renal. Symptoms of type 1 diabetes can start quickly, in a matter of weeks.
It is the second leading cause of blindness and renal disease worldwide. It also affects how the body responds to blood sugar. Global report on diabetes world health organization. Symptoms of type 2 diabetes often develop slowlyover the course of several yearsand can be so mild that you might not even notice them. Diabetes mellitus dm also known as simply diabetes, is a group of metabolic diseases in which there are high blood sugar levels over a prolonged period this high blood sugar produces the. The manifestations of diabetes cause considerable human suffering and. It often causes only mild high blood sugar hyperglycemia. National clinic guidelines for management of diabetes. Type 2 diabetes may account for about 90 percent to 95 percent of all diagnosed cases of diabetes. It causes confused thinking, weakness, nausea and even seizure and coma. Definition diabetes mellitus is a condition in which the pancreas no longer produces enough insulin or cells stop responding to the insulin that is produced, so that glucose in the blood. Type 1 diabetes mellitus t1dm, also known as autoimmune diabetes, is a chronic disease characterized by insulin deficiency due to pancreatic. High blood glucose levels are symptomatic of diabetes mellitus as a consequence of. Pulmonary function reduction in diabetes with and without chronic obstructive.
Diabetes mellitus, also called diabetes, is a term for several conditions involving how your body turns food into energy. Diabetes mellitus is a chronic metabolic disorder characterized by high blood sugar hyperglycaemia. The discussion was closed on 25 may 2011 with a consensus to merge. Every age group was observed for 5 weeks during which fasting glucose was measured every second day. Risk factors for type 2 diabetes include older age, obesity, family history of diabetes, prior history of gestational diabetes, impaired.
What is diabetes mellitus and what are the symptoms. Things are different in type 2 diabetes, where insulin is made by the pancreas but. In the weightcausesdiabetes framing and in the creation of a new condition diabesity in which the two fully merge. Note that there is a subtle difference between causes and risk. Efforts to improve capacity for diagnosis and treatment of diabetes should. What is known is that your immune system which normally fights harmful bacteria or viruses attacks and destroys your insulinproducing cells in the pancreas. Management of noninsulindependent diabetes mellitus niddm requires teamwork. Increase, switch, or combine drugs targeting at hba1c 6. The goal of diabetes treatment is to secure a quality of life qol and. Approximately 40% of the familial aggregation of type 1 diabetes can be.
1391 430 1533 981 1170 941 150 1235 767 151 1397 603 1472 1321 104 1297 896 230 1517 1116 496 186 1017 560 665 911 1220 197 1203 956 723 848 342 418 1291 836 895 552 716 1185 1320 644 96 572 1205 1430 662